Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: unusual or rapid weight gain, unusual or severe mentalmood changes. Sertraline, sold under the trade name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Zoloft, generically known as sertraline, belongs to a category of antidepressants known as Selective Serotonin Reuptake Inhibitors, or SSRIs. I have not taken that drug but I can tell you that there are many drugs available that say they do not cause weight gain, but they most surely do. Review of the most common prescription drugs and drug classes that may lead to weight gain. Menopause, by definition, is the absence of menstrual periods for 12 consecutive months. The age of onset varies for each woman. Menopause symptoms include hot. While many people lose a pound or two while on Zoloft, others lose too much weight when taking the drug. This eMedTV resource discusses Zoloft and weight loss, and. Agarwal says selective serotonin reuptake inhibitors (SSRIs)such as Prozac, Zoloft, and Paxilare some of the biggest weightgain offenders. weight loss, especially in underweight depressed or bulimic individuals, may be an unwanted effect of treatment with Prozac. Seroquel (Quetiapine) is a popular atypical antipsychotic medication that has been approved by the FDA to treat schizophrenia, bipolar disorder, and as an. Selective serotonin reuptake inhibitors (SSRIs) generally don't cause weight gain because the antidepressants boost serotonin, which helps you feel full. Everything You Need to Know About Antidepressants That Cause Weight Gain Continued Antidepressants and Weight. Another, less welldocumented side effect of antidepressants is weight gain. Go on any health message board and you. Zoloft (sertraline generic) is a prescription drug used to treat depression, obsessivecompulsive disorder, panic disorder, PTSD, social anxiety disorder. These highlights do not include all the information needed to use ZOLOFT safely and effectively. See full prescribing information for ZOLOFT. Canine pancreatitis is inflammation of the pancreas that can occur in two very different forms. Acute pancreatitis is sudden while chronic pancreatitis is. Get Health Facts Prescription Drugs Causing Weight Gain?.