• . 25 mg filmcoated tablets Summary of Product Characteristics (SmPC) by Generics UK TA Mylan General Pharmacology. Currently approved calciumchannel blockers (CCBs) bind to Ltype calcium channels located on the vascular smooth muscle, cardiac myocytes, and. Felodipine official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. A number of drug classes are effective for initial and subsequent management of hypertension. For drug selection and use in treatment of stable. Cardioplen XL 5mg Prolonged Release Tablets contain 5mg of felodipine. Cardioplen XL 5mg Prolonged Release Tablets contains 23. 95mg of lactose monohydrateprolonged. Metoprolol Succinate official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. According to manufacturer, it is not known whether felodipine is excreted into human milk, and therefore, breastfeeding should be discontinued during felodipine. Diltiazem, sold under the trade name Cardizem among others, is a calcium channel blocker used to treat high blood pressure, angina, and certain heart arrhythmias. Plendil ER Data Sheet Copyright Doc ID v1 4 4. 7 EFFECTS ON ABILITY TO DRIVE AND USE MACHINES Felodipine is not likely to affect the ability to drive. When a person takes excessive amounts of metoprolol, overdose symptoms may occur, including extremely low blood pressure, tiredness, or severe decrease in heart rate. SIDE EFFECTS; SLOW HEART RATE (BRADYCARDIA) Verapamil and diltiazem can slow the heart rate; The effect can be additive with other medications that also slow the. Because beta blockers, like pindolol, depress conduction through the AV node, these drugs are contraindicated in patients with severe bradycardia or advanced AV block.