For decades, womens health advocates have been concerned about the safety of DepoProvera, the progesteronebased contraceptive shot (the shot). Many people who use hormonal birth control cite weight gain as a side effect. Learn what the research says about birth control and weight gain. DepoProvera is an injection used to prevent pregnancy. A form of this medication may also be used to treat endometriosis. The shot is just what it sounds likea shot that keeps you from getting pregnant. Once you get it, your birth control is covered for three full monthstheres. Many women who take Depo Provera experience weight gain, according to Virginia Commonwealth University. Since this contraceptive only contains progesterone. Here, seven birth control shot side effects you should be aware of before you make your choice. Some women report withdrawal symptoms after stopping DepoProvera, a progesteroneonly contraceptive method that is injected quarterly. Dietitian, Juliette Kellow gives advice on weight gain and loss with the Depo Provera contraception injection. The Depo Provera injection is a form of longacting reversible contraception for women. This page explains how the injection works and tells you how to get it. How To Detox From Depo Provera Shot Home Exercises That Burn Fat How To Detox From Depo Provera Shot La Weight Loss Fat Burner Fat Burner Smoothie Before Or After. Women who use DepoSubQ Provera 104 may lose significant bone mineral density. Bone loss is greater with increasing duration of use and may not be. is a type of brandname, injectable birth control that can effectively prevent pregnancy for up to three months. Rachel, thanks for writing a followup post to your November 2009 post about the challenges women are facing coming off DepoProvera. These highlights do not include all the information needed to use DEPOPROVERA CI safely and effectively. See full prescribing information for DEPOPROVERA CI. Before starting on DepoProvera the doctor will need to know if: There is the possibility you might be pregnant; You have liver or heart problems, seizures, diabetes.